Each tube is enough for 16 fl oz of cream or lotion at approximately 1% concentration (5 g in 480 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base. Leave on overnight for use as a cream or rinse after 30 minutes for use as a mask.

It is said that as a tea, Jiaogulan would "benefit Qi, enrich the blood, keep the heart in good shape, and relieve uneasiness of body and mind". Gypenosides isolated from Gynostemma Pentaphyllum are widely used in traditional Chinese medicine, with beneficial effects reported in numerous diseases, including inflammation and atherosclerosis. The mechanism underlying these therapeutic effects is unknown but suppression of NO synthesis may be involved.

For those who want scientific information rather than Qi: Jiaogulan Extract can absorb UV (increasing the SPF of any sunblock), gypenosides can protect vascular endothelial cells from oxidant injury, and it may further slow the aging process.

Active ingredient in Freeze 24/7™ line.

Aktan, Fugen; Henness, Sheridan; Roufogalis, Basil D.; Ammit, Alaina J (2003) Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF- B-mediated iNOS protein expression. Nitric Oxide, 8: 235-242. Li L; Jiao L; Lau B H (1993) Protective effect of gypenosides against oxidative stress in phagocytes, vascular endothelial cells and liver microsomes. Cancer biotherapy 8: 263-72. Li, Lin; Lau, Benjamin H. S. (1993) Protection of vascular endothelial cells from hydrogen peroxide-induced oxidant injury by gypenosides, saponins of Gynostemma pentaphyllum. Phytotherapy Research, 7: 299-304.