In our cells, we have our own SODs, but we can protect our skin by supplementing them with topically applied SOD. The size of the SOD used in skin care varies between 10,000 and 30,000 molecular weight, relatively small for an enzyme but large enough to be excluded from live cells. The fact that SOD is unlikely to enter live cells is not a problem. Lipid peroxidation occurs everywhere in the skin, not just in the live cells. The role of SOD is to eliminate the free radicals resulting from lipid peroxidation and to prevent the chain reactions that would eventually reach deeply into the skin, and topical application of SOD will certainly help to achieve this aim.

Superoxide radicals are formed in a number of metabolic reactions, including lipid peroxidation initiated by light or metal ions. This process is the cause of rancidity of oils, but it also happens in live tissues and may be a cause of cancer, inflammatory diseases, atherosclerosis, aging, and others.

One of the reasons that superoxide radicals are so dangerous is because they start chain reactions where more and more free radicals are formed, reacting with all cell constituents and wreaking havoc wherever they go. In the human body, the main chain breaking antioxidants are the water soluble Superoxide Dismutase (SOD) and the lipid soluble alpha-D-Tocopherol (vitamin E). SOD is a particularly stable enzyme that converts the destructive superoxide radical into a less dangerous form, hydrogen peroxide (which will, in turn, be converted into water and normal oxygen by the enzyme catalase).

This is one the specialty proteins (see also EGF and KGF) made by Skin Actives Scientific. 

Please ask us about wholesale pricing as well as custom protein development.

Each kit is enough for 4 fl oz of cream, lotion, or serum at approximately 0.0001% concentration (100 mcg in 120 mL cream). Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base. Mix thoroughly, but gently. Vigorous mixing will decrease the activity level of the SOD.

We keep SOD highly concentrated to preserve its activity, therefore you will hardly see the SOD drop at the bottom of the small tube. Store the SOD in the refrigerator until you are ready to use it. When ready to use, add the contents of the second tube (saline solution) to the tube containing SOD and close. Mix by inverting and straightening the tube several times. The SOD is now ready for addition to your cream, lotion, or serum. This enzyme is very active, and one microgram, one millionth of a gram, will go a very long way.

Solubility Hydrophilic

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