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SKU 182

Quantity Price
10-24 Items $8.93
25+ Items $8.40

Skin Concern: Anti-aging, redness and irritation

Skin Type: All skin types

Dr. Sivak's Notes:

• This antioxidant found in grapes and red wine protects from oxidative stress and reduces the look of fine lines and wrinkles.

Plant polyphenols like resveratrol benefit the skin by reducing irritation and supporting cell revitalization through their interaction with growth factor receptors.

• Find this in our ready made Anti-Aging Cream.


Purchase 10 or more for an automatic discount. Other sizes available upon request at

Anti-Aging     Healthy Skin    
Paraben Free Actives    
Animal Free Actives    
Water & Cream Soluble    
Product Style Do It Yourself    

Each tube is enough for 8 fl oz of cream or lotion at approximately 1% concentration (2.5 g in 240 mL cream), so use about 1.2 g in 4 oz of cream. Use in your favorite cream or add to our Canvas Base Cream or our Sea Kelp Coral.


Resveratrol has been shown to have many beneficial effects on human health, and the possible connection between resveratrol and calorie-restricted diets in extending life has been a minor aspect of the research into its mechanism of action.*


Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic antioxidant, found in grapes and red wine, that blocks UVB-mediated activation of the factor NFkappa-B. Plant polyphenols like resveratrol benefit the skin with anti-inflammatory and wound healing activity through their interaction with growth factor receptors (and the cytoplasmic and nuclear pathways these receptors control) rather than through direct redox properties.*


(*See reference tab for scientific resources)


Adhami, V.M. ; Afaq, F.; Ahmad, N. (2003) Suppression of ultraviolet B exposure-mediated activation of NF-?B in normal human keratinocytes by resveratrol. Neoplasia, 5:74-8

Bernard, P.; Berthon, J.-Y.(2000) Resveratrol: An original mechanism on tyrosinase inhibition International Journal of Cosmetic Science 22: 219-224.

Ndiaye, M.; Philippe, C; Mukhtar, H; Ahmad, N (2011) The grape antioxidant resveratrol for skin disorders: Promise, prospects, and challenges. Archives Biochemistry Biology (Biochemistry and Biophysics of the Skin), 508:164–170

Pastore, S, Lulli, D, Fidanza, P, Potapovich, A I., Kostyuk, V A.; De Luca, C; Mikhal'Chik, E; Korkina, L.G. (2012) Plant Polyphenols Regulate Chemokine Expression and Tissue Repair in Human Keratinocytes Through Interaction with Cytoplasmic and Nuclear Components of Epidermal Growth Factor Receptor System. Antioxidants and redox signaling, 16: 314-328.

Wolter, F.; Stein, J. (2002) Biological activities of resveratrol and its analogs. Drugs of the Future, 27: 949-959.

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