Application of Niacinamide topically has been shown to benefit skin color, decrease melanin synthesis (important for hyperpigmentation), and decrease inflammation and itching (pruritus).

The biochemical effects of Niacinamide include increased concentration of NADPH, the donor of reducing power in cell biosynthesis, an effect that translates into increased synthesis of collagen, involucrin, filaggrin, and keratin.

Topical application of Niacinamide also decreases UV-induced skin cancers and prevented immunosuppression by UV irradiation.

Niacinamide (nicotinamide for chemists) is part of a coenzyme essential for metabolism. Because we cannot make it, we must acquire Niacinamide from outside sources, making it by definition, a vitamin. Even if we obtain enough Niacinamide through food and multivitamin supplements, application topically is beneficial. As skin ages, the body no longer supplies enough nutrients to the skin, partly because the density of blood vessels reaching the dermis decreases.

The effect of Niacinamide on inflammation is through inhibition of histamine release by mast cells, neutrophil chemotaxis, and release of inflammatory mediators. Niacinamide will also help with skin infections in diabetics.

Each tube is enough for 32 fl oz of cream or lotion at approximately 0.5% concentration (5 g in 960 mL cream) or 5% when the whole tube is added to 4 oz cream or gel. Use in your favorite cream or add to our Canvas Base Cream or a Sea Kelp Bioferment base.

Warning

Please note that application of niacinamide is contra-indicated for people affected by Parkinson disease.

Warning Please note that application of niacinamide is contra-indicated for people affected by Parkinson disease

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Customer Reviews

• Author: Terrie
  I ordered "Niacinadmide" and "Allantoin" and added them to a nice aloe vera gel, which I use every morning after cleansing. The gel is soothing and dries to a nice matte finish in lieu of shiny; it really cuts down on break-outs, I love it! **Niacinamide, touted for it's skin-lightening affect also has anti-acne and anti-aging properties.**
• Author: Regina
  I just recieved my order yesterday. So yesterday night I mixed about 6 scoops of the Niacinamide into my daily moisturizer. I used the little plastic scooper it came with. Trust me, I was very skeptical, but already this morning I can see my skin feels smoother, has a little glow to it, and some pimples I had just yesterday have seemed to diminish! I am really impressed, and look forward to seeing the long term results!
• Author: Marites
  I discovered skinactives when I was looking for niacinamide powder. I recently read that by mixing 5% of it with 2 oz. of aloe vera , it is the same as using strong anti-biotics for treatment in adult acne but with no side effects. So I bought one and made my concoction. I've been using it for 2 weeks now after a massive acne break out mostly around my jawline and below the neck, my face is less inflamed and the readness had tremendously subsided. I will continue using this for now as it is working.
• Author: Annelle
  A little of this in the Canvas Base Cream, used every morning after cleansing controls my rosacea flares better than the prescriptions did. I love this product, and my dermatologist is amazed.