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Niacinamide (Vitamin B3)

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SKU 168

Quantity Price
10-24 Items $6.80
25+ Items $6.40

Skin Concern: Dark spots, redness and irritation, anti-aging

Skin Type: All skin types

Dr. Sivak's Notes:

Helps eliminate the formation of dark spots and uneven skin tone.

• Reduces redness, irritation and dryness.

• Helps to maintain the synthesis of collagen, involucrin, filaggrin, and keratin.

Application of Niacinamide is contraindicated for people affected by Parkinson's disease.


Purchase 10 or more for an automatic discount. Other sizes available upon request at

Acne & Blemishes     Anti-Aging     Dark Spots     Redness & Irritation    
Paraben Free Actives    
Animal Free Actives    
Product Style Do It Yourself    
Water & Cream Soluble    

Each tube is enough for 32 fl oz of cream or lotion at approximately 0.5% concentration (5 g in 960 mL cream) or approximately 5% when the whole tube is added to 4 oz cream or gel. Use in your favorite cream or add to our Canvas Base Cream or our Sea Kelp Coral.

Warning: Please note that application of niacinamide is contraindicated for people affected by Parkinson's disease.


The biochemical effects of Niacinamide include increased concentration of NADPH (the donor of reducing power in cell biosynthesis), an effect that translates into increased synthesis of collagen, involucrin, filaggrin, and keratin.*


This molecule is one of the components of NADPH (reduced niacinamide adenine dinucleotide phosphate), the coenzyme that provides the reducing power required to build new molecules in the human body. Niacinamide and niacin are not synthesized in the human body and, therefore, must be supplied externally (this is why we call niacin a vitamin) either through the diet or through topical application.*


Niacinamide is also part of NAD (like NADP but without the extra phosphate), the molecule that is found wherever carbohydrates and other foodstuffs are oxidized (respired) to make energy. Even when following a normal healthy diet, topical application of niacinamide will result in increased synthesis of collagen, keratin, involucrin, and filaggrin. Topical application of niacinamide will decrease pruritus and inflammation, help acne affected skin, decrease oiliness, alleviate atopic dermatitis and help decrease facial pigmentation. These are just a few of the beneficial effects of topical application of niacinamide to the skin, and it would be suspicious that there are so many were it not for the crucial role of this chemical in human metabolism.*


(*See reference tab for scientific resources)


Bissett, Donald L.; Oblong, John E.; Berge, Cynthia A. Niacinamide: a B vitamin that improves aging facial skin appearance Dermatologic Surgery (2005), 31: 860-865.

Namazi, Mohammad R. Nicotinamide in dermatology : a capsule summary. International Journal of Dermatology (2007), 46: 1229-1231.


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Customer Reviews**

  • Author: Terrie
    I ordered "Niacinadmide" and "Allantoin" and added them to a nice aloe vera gel, which I use every morning after cleansing. The gel is soothing and dries to a nice matte finish in lieu of shiny; it really cuts down on break-outs, I love it! **Niacinamide, touted for it's skin-lightening affect also has anti-acne and anti-aging properties.**
  • Author: Regina
    I just recieved my order yesterday. So yesterday night I mixed about 6 scoops of the Niacinamide into my daily moisturizer. I used the little plastic scooper it came with. Trust me, I was very skeptical, but already this morning I can see my skin feels smoother, has a little glow to it, and some pimples I had just yesterday have seemed to diminish! I am really impressed, and look forward to seeing the long term results!
  • Author: Marites
    I discovered skinactives when I was looking for niacinamide powder. I recently read that by mixing 5% of it with 2 oz. of aloe vera , it is the same as using strong anti-biotics for treatment in adult acne but with no side effects. So I bought one and made my concoction. I've been using it for 2 weeks now after a massive acne break out mostly around my jawline and below the neck, my face is less inflamed and the readness had tremendously subsided. I will continue using this for now as it is working.
  • Author: Annelle
    A little of this in the Canvas Base Cream, used every morning after cleansing controls my rosacea flares better than the prescriptions did. I love this product, and my dermatologist is amazed.
  • Author: Paula Boulanger
    I take the birth control pill which will give me a bit of hyperpigmentation if I don't stay out of the sun, wear a good physical block when I can't avoid it and alternate between this and the l-ascorbic acid. I mix it into a simple pleasant smelling cream that I enjoy, add some astaxanthin and voila!


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