Granulysin is a member of lysosomal proteins (saposins-like) that function as activator of various lysosomal lipid-degrading enzymes. Granulysin is expressed by activated human killer cells and T-lymphocytes and it exhibitsactivity against Gram-positive and Gram-negative bacteria and fungi. Granulysin is a protein of small molecular weight that can be delivered in a cream or lotion that will help keep pores open, preventing the formation of comedos.  One of the advantages of this particular protein is that it will help keep the acne bacteria, Propionibacterium acnes, at bay.

Granulysin is a member of lysosomal proteins (saposins-like) that function as activator of various lysosomal lipid-degrading enzymes. Granulysin is expressed by activated human killer cells and T-lymphocytes and it exhibits activity against Gram-positive and Gram-negative bacteria and fungi. Granulysin is a protein of small molecular weight that can be delivered in a cream or lotion that will help keep pores open, preventing the formation of comedos. One of the advantages of this particular protein is that it will help keep the acne bacteria, Propionibacterium acnes, at bay.

Add to 4 ounces of cream or serum. Granulysin can be found in our ready to use zit ender (http://www.skinactives.com/Zit-Ender.html)

Bleackley, R. C., Lobe, C. G., Duggan, B., Ehrman, N., Fregeau, C., Meier, M., Letellier, M., Havele, C., Shaw, J., Paetkau, V. (1988) The isolation and characterization of a family of serine protease genes expressed in activated cytotoxic T lymphocytes Immunol. Rev. 103,5‐19. Jenne, D. E., Masson, D., Zimmer, M., Haefliger, J‐A., Li, W‐H., Tschopp, J. (1989) Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases Biochemistry 28,7953‐7961. Jenne, D. E., Tschopp, J. (1988) Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation Immunol. Rev. 103,53‐71. Jongstra, J., T J Schall, B J Dyer, C Clayberger, J Jorgensen, M M Davis, A M Krensky (1987) The isolation and equence of a novel gene from a human functional T cell line. J. Exp. Med . 165:601‐614.

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