Granulysin is a special active protein developed by Skin Actives to target blemish-prone skin. It is a member of lysosomal proteins and it will help keep at bay the bacteria, Propionibacterium acnes, by creating holes in the target cell membrane. To use this DIY ingredient to help prevent and eliminate blemishes, simply add one tube of Granulysin to 4oz of your favorite moisturizing cream or water-based serum and mix gently.
Learn more about Granulysin and other active ingredients we use for blemishes in our blog.
How to use it
Beginner: Add 1 tube to 4 oz of your favorite base cream or water-based formula.
Advanced: This ingredient is recommended for use at about 0.00005% in formulations. Carefully add this solution during the cool down phase of formulation with gentle mixing. This ingredient is soluble in creams and water-based products, but not recommended for use in anhydrous products.
Quick Tips
Store product in fridge. Do not freeze.
Ingredients
Products with this ingredient:
Zit Ender
INCI:
sh-Polypeptide-108
Research
Bleackley, R. C., Lobe, C. G., Duggan, B., Ehrman, N., Fregeau, C., Meier, M., Letellier, M., Havele, C., Shaw, J., Paetkau, V. (1988) The isolation and characterization of a family of serine protease genes expressed in activated cytotoxic T lymphocytes Immunol. Rev. 103,5‐19.
Jenne, D. E., Masson, D., Zimmer, M., Haefliger, J‐A., Li, W‐H., Tschopp, J. (1989) Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases Biochemistry 28,7953‐7961.
Jenne, D. E., Tschopp, J. (1988) Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation Immunol. Rev. 103,53‐71.
Jongstra, J., T J Schall, B J Dyer, C Clayberger, J Jorgensen, M M Davis, A M Krensky (1987) The isolation and equence of a novel gene from a human functional T cell line. J. Exp. Med . 165:601‐614.