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Body Part Body     Face     Feet     Hands    
Product Style Do It Yourself    
Solubility Cream     Liquid (Water)    
Age 20s/30s     40s/50s     60+    
Ingredient Type Lab Designed     Paraben Free     Powder     Vegan    
Need/Issue Skin Tightening    

DMAE Bitartrate

$4.50

Size

SKU 122

DMAE improves the firmness of the skin and helps reduce the visual appearance of sagging skin. It is the signature ingredient in our ready to use 4% DMAE Serum.

DMAE is a frequent ingredient in Perricone's products.

Note: DMAE Bitartrate contains a lot of salt, therefore it has a tendency to dry out the skin. Please do not use if you already have very dry skin, or be sure that you use a moisturizer to keep skin healthy.

Body Part Body     Face     Feet     Hands    
Product Style Do It Yourself    
Solubility Cream     Liquid (Water)    
Age 20s/30s     40s/50s     60+    
Ingredient Type Lab Designed     Paraben Free     Powder     Vegan    
Need/Issue Skin Tightening    

In the May 2015 Newsletter, Dr. Sivak gave some more information on the controversy around DMAE. Here is what she has to say, "DMAE improves the firmness of the skin and helps reduce the visual appearance of sagging skin, although the mechanism of action is unknown. It is an amine-based alcohol, a precursor to the neurotransmitter acetylcholine, present in nerve tissue in small amounts and more abundant in fish. DMAE acts as a free radical scavenger due to the high electron content of its nitrogen atom. Once phosphorylated, DMAE is incorporated into the membrane of cells. In addition, DMAE is an immediate precursor to choline, which is involved in cell membrane biosynthesis. 

At SAS we sell DMAE as DMAE bitartrate, a salt of DMAE (DMAE is strongly alkaline and hazardous to ship and manipulate), so take into account that the actual percentage of DMAE by weight in the salt is about 37%, i.e., 100 grams of DMAE bitartrate contain 37 grams of DMAE. To make 4oz (120 mL) of serum containing 3% DMAE, you will need about 10 gm DMAE bitartrate (the rest will be the tartaric acid).

In the last few years, many people have been using DMAE. An article was published in a scientific journal that should not have passed the reviewers, but it did. Like all scary information about chemicals present in our daily life, the information was amplified by the social media using the internet and it became a big event. It should not have, because dramatic results that contradict decades of results should be vetted carefully. After all the foam dissipated, everybody went back to using DMAE. I always had mixed feeling about DMAE because its mechanism of action is not understood, i.e. we do not know how it increases skin firmness. But, until somebody comes up with better information, we have to assume that DMAE used by our clients (up to 4% in a compatible serum) is perfectly fine."

 

DMAE is an amine-based alcohol, a precursor to the neurotransmitter acetylcholine, and is present in nerve tissue (in small amounts) and is more abundant in fish.

DMAE acts as a free radical scavenger due to the high electron content of its nitrogen atom. Once phosphorylated, DMAE is incorporated into the membrane of cells, protecting against cell membrane protein cross-linking. In addition, DMAE is an immediate precursor to choline, which is involved in cell membrane biosynthesis.

The mechanism of action of DMAE by which it increases skin firmness is unknown.

The actual percentage of DMAE by weight in the DMAE bitartrate salt is about 37%. To achieve a concentration of 3% DMAE in 4 oz (120mL) of your formulation, you will need about 10 g DMAE bitartrate (the rest will be the tartaric acid).

DMAE Bitartrate added directly to a base cream will probably turn the cream into a runny lotion. To prepare a DMAE cream, mix the DMAE first with Sea Kelp Coral, then combine the mixture with the cream. Try a little at a time so that your cream does not liquify, unless you don't mind using it as a lotion

DMAE bitartrate.

Customer Reviews**

  • Author: TINA
    I LOVE to add this to a spray small spray bottle with Aloe and use as a face toner. The DMAE makes the Aloe watery so it sprays well. I also add some GAMMA and Dermagen & a drop or 2 of the ANTI-OX to it, just a little, to give it a boost and I spray it on whenever I don't have any make-up on. Great stuff.
  • Author: Pia Francesca
    This is a must have active. I add this to all my creations, lotions, creams and serums that are for wrinkle reduction. DMAE Instantly creates a

**Results may vary

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