Arbutin is the natural alternative to hydroquinone, present in the leaves of the bearberry. Use of pure arbutin in skin care products is patented and licensed, limiting consumer choice and increasing the price of the products containing it.

This product is an ingredient in the following skin care lines: Shiseido Whitess.

Note: Arbutin is used at 5% in Shiseido Whitess.

Each tube is enough for about 4 fl oz of cream or lotion at 5% concentration (6 g in 120 mL cream) and can be combined with our other actives. The powder will not dissolve immediately but will release components slowly into the cream or lotion. Use in your favorite cream or add to our Canvas Base Cream, European Cream, or our Sea Kelp Ultramarine.

For best results, we suggest a concentration of 1.5% (1.8 gm) in 4 oz of cream working synergistically with other skin lighteners like our Kojic Acid Dipalmitate, Betulinic Acid, and Niacinamide. The different actives will target different steps of the melanin synthesis and delivery pathway.

Tomita, Kenichi; Fukuda, Minoru; Kawasaki, Kiyoshi (1990) Mechanism of arbutin inhibitory effect on melanogenesis and effect on the human skin with cosmetic use. Fragrance Journal (1990), 18: 72-7. Siegers, C. P.; Siegers, J. P.; Pentz, R.; Bodinet, C.; Freudenstein, J. (1997) Metabolism of arbutin from Uva ursi-extracts in humans. Pharmaceutical and Pharmacological Letters 7: 90-92. Jin, Ying Hua; Lee, Suk Jin; Chung, Myung Hee; Park, Jeong Hill; Park, Young In; Cho, Tae Hyeong; Lee, Seung Ki. (1999) Aloesin and arbutin inhibit tyrosinase activity in a synergistic manner via a different action mechanism Archives of Pharmacal Research 22: 232-236. Maeda, Kazuhisa; Fukuda, Minoru (1996) Arbutin: mechanism of its depigmenting action in human melanocyte culture. Journal of Pharmacology and Experimental Therapeutics 276: 765-9.

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